What Are The Triggers Of Low Anion Gap? 13 Common Causes

Lithium Toxicity

Low Anion Gap Metabolic Acidosis is a potentially life-threatening condition caused by lithium toxicity. Lithium is a medication used to treat bipolar disorder, and while it is effective at managing the condition, it can also be deadly if not properly monitored. 

When lithium levels in the blood become too high, it can cause Low Anion Gap Metabolic Acidosis. This condition occurs when there is an accumulation of acidic substances in the blood and tissues. Symptoms of Low Anion Gap Metabolic Acidosis include confusion and coma. Low Anion Gap Metabolic Acidosis can lead to organ failure and death if left untreated. 

The exact mechanism by which lithium toxicity causes Low Anion Gap Metabolic Acidosis is not fully understood. However, it is believed that lithium interferes with kidney function. This interference with kidney function may also explain the other symptoms associated with Low Anion Gap Metabolic Acidosis, such as nausea, vomiting, and abdominal pain. 

The best way to prevent Low Anion Gap Metabolic Acidosis is to closely monitor lithium levels in the blood and adjust the dose accordingly. Talking to a doctor about the risks and how to best avoid them is best.