What Could Cause High Bilirubin? 13 Possible Triggers (List)

Gilbert’s Syndrome

A condition known as Gilbert’s syndrome causes the amounts of bilirubin to accumulate in the blood at slightly higher than usual levels. Gilbert’s syndrome is a form of hereditary liver disease passed down from generation to generation that impairs the body’s capacity to handle bilirubin. As a result, people with Gilbert’s syndrome do not create enough liver enzymes, which prevents their bilirubin levels from being within the normal range. Because of this, an abnormal amount of bilirubin accumulates in the body. Hyperbilirubinemia is the medical term for having an excessive amount of bilirubin.

Jaundice, brought about by abnormally high amounts of bilirubin in the blood, is the sign that occurs most frequently among all of the symptoms. Gilbert syndrome is due to gene mutation. This gene regulates an enzyme responsible for the liver’s breakdown of bilirubin. A defective gene causes the body to create an insufficient quantity of the enzyme, resulting in high bilirubin levels. The defective gene prohibits bilirubin in the blood from flowing into the bile at the typical pace and accumulates in circulation. It causes a yellowish cast to appear on the skin and the whites of the eyes.