Fatigue
One of the most common, the first sign for many people, is fatigue or exhaustion. The patient may feel extremely tired and weak all the time. Some patients also experience muscle aches along with it.
To understand how this symptom works, we must first understand what causes fatigue. Fatigue is one of the symptoms that can an infection stimulates an immune system response by an infection. The body’s defense system responds to diseased cells or invading organisms by releasing chemicals into the bloodstream to combat them. These chemicals include histamine and interleukins, which cause inflammation in the blood vessels and tissue surrounding them.
This inflammation causes blood vessels to leak fluid into tissues and organs throughout the body, which makes patients feel exhausted after long periods of activity. The body needs time to recover from this reaction and replenish its fluids. This creates a vicious cycle where infections or other stimuli continually activate the body’s defense system. The more it is activated, the stronger its response becomes, which can lead to chronic inflammation and a host of other problems in the long run.
The onset of fatigue in syphilis can start as a mild feeling of exhaustion but can worsen over time to the point where it’s difficult to get out of bed, and the individual feels like moving at all is impossible.
