Hormonal Shifts
Excessive sweating from the eccrine sweat glands in the feet can also happen due to fluctuations in hormone levels or hormonal shifts. The eccrine gland sweat secretion occurs when calcium ions from extracellular cells are stimulated and activated in the luteal phase, causing overactivity of the working excretory ducts of the cuboidal cells in the deep dermis. Such activity is typically regulated by nerves and hormones and may vary depending on gender.
For women, such hormonal shifts occur during the second phase of the post-ovulation cycle, when progesterone and estrogen levels rise and fall. This fluctuation usually influences the hypothalamus, which, in turn, causes the brain center in charge of thermoregulation to go haywire due to the imbalance in hormones. When the imbalance between progesterone and estrogen becomes significant enough, and the progesterone gets too high, the body temperature rises, causing hot flashes and sweating. This condition can be observed as the body compensates for heat loss and adjust to the stress caused by the imbalance.
While this condition is expected during the menopausal and perimenopausal stages, it can affect women of all ages and, at times, even men.
