Pruritus and Xanthelasma
The liver filters bile salts and neutralizes toxins. These substances may build up in the body if their function is compromised, and their accumulation in the skin leads to irritation and itching. Pruritus, the medical term for itchy skin, is a common symptom of liver diseases such as fatty liver disease and is often worst on the hands and feet. Reducing bile salt levels may alleviate pruritus symptoms, although there is no correlation between bile salt levels and pruritus severity. Itching and pruritus brought on by liver disease are difficult to remedy and often alleviated as the NAFLD is being treated.
On the other hand, hypercholesterolemia or dyslipidemia is a lipid disorder characterized by an abnormally high concentration of bad cholesterol (LDL). It often manifests as xanthelasma, a localized cholesterol deposit under the skin, most noticeable around the eyelids. Most cases of xanthelasma manifest as a painless, yellowish, soft plaque with well-defined borders that may grow in size over weeks.
Fatty liver disease is commonly accompanied by an abnormally high amount of triglycerides in the blood and low levels of HDL cholesterol, the most prevalent symptoms of fatty liver disease and dyslipidemia. According to studies, half or more individuals with liver dysfunction had an abnormally high total plasma cholesterol level.
