14 Causes & Triggers of Mouth Sores You Shouldn’t Ignore (List)

Celiac Disease

Gluten is a prolamin protein in most grains that causes immunological responses in patients diagnosed with celiac disease. Symptoms of celiac disease can be felt in the oral region, including tooth enamel abnormalities and chronic canker sores. Pitting, grooving, and even total loss of enamel are all visible forms of enamel defect accompanied by canker sores. Aphthous ulcers, or canker sores, are prevalent in people with celiac disease and can become infected and painful. Sometimes these lesions are the only sign of celiac disease in patients and can be traced back to an autoimmune reaction. 

Celiac mouth lesions can be distinguished from other mouth sores by their whitish color, and they are usually located on the tongue and inside the cheeks. Also, they are accompanied by diarrhea, skin rashes, bloating, and headaches. On the other hand, when the small intestinal lining is damaged due to celiac disease, the body cannot properly absorb essential nutrients. Because the duodenum in the small intestine is responsible for iron absorption and is also the area of the digestive tract most negatively affected by gluten, celiac disease can lead to iron deficiency anemia and vitamin B12 deficiency. These conditions are associated with symptoms of mouth sores.