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Bupleurum

A herbal supplement from Bupleurum Chinense, Bupleurum has been widely used in Japanese and Chinese medicine to treat various illnesses, including liver conditions. While additional studies are necessary, animal research in 2017 suggests it could possess curative and hepatoprotective effects on liver damage. Its popularity in western countries has recently surged thanks to its potential liver-cleansing benefits. However, some studies also indicate that it may support the immune system’s health and fight inflammation.

The herb may prevent neuropathy, a relatively common complication for those with diabetes. A six-week study involving rats showed bupleurum reduces blood sugar, lowers inflammation, and improves gut microbiota. Research also indicates that it may strengthen the immune system’s health. A human study compared it to common antiviral medication and found it effective as a treatment method for influenza without adverse effects.

However, the downside is that the herb may have potential dangers when taken at high doses. In a review, bupleurum’s primary compound, saikosaponins, had been found to cause lesions and inflammation of the liver when consumed excessively for short periods. It may also interact with and impact other medications and herbal supplements, resulting in other side effects.