Inclusion body myositis
Inclusion body myositis (IBM) is a rare condition that causes muscle weakness and damage. The progressive weakness in the hand, forearm, thigh and lower leg muscles is caused by damage to muscle fibers. In inclusion body myositis, it can be challenging to diagnose because the symptoms are not unique to this condition.
People with inclusion body myositis may have elevated liver enzymes such as alanine transaminase (ALT) and aspartate transaminase (AST). The elevated liver enzymes in inclusion body myositis patients are thought to be caused by the buildup of abnormal proteins in the liver. Moreover, the elevated Liver enzymes can also signify that the person has another myositis-related condition, such as autoimmune hepatitis or primary biliary cirrhosis.
The treatment for elevated liver enzymes in people with inclusion body myositis will depend on the underlying cause of the elevated liver enzymes. If the elevated liver enzymes are due to inclusion body myositis, the treatment will focus on managing this condition. If the elevated liver enzymes are due to another myositis-related condition, the treatment will focus on addressing that condition.
