Alagille Syndrome
Alagille syndrome is a hereditary disorder that affects the liver and other organs. The condition is caused by a protein defect that helps transport bile from the liver to the small intestine. This can cause a build-up of bile in the liver, damaging the liver cells and leading to cirrhosis.
Alagille syndrome is a genetic disorder passed down from parents to children. The condition is most common in people of Asian descent. The most common symptom of Alagille syndrome is jaundice, caused by a build-up of bilirubin in the blood. Bilirubin is a yellowish pigment produced when red blood cells are broken down. Other symptoms of the disorder may include growth retardation, abdominal pain, gallstones, and kidney abnormalities.
Treatment for the condition typically involves a multidisciplinary approach that includes close monitoring by a team of specialists. In some cases, medications may be prescribed to help relieve symptoms or improve liver function. Surgery may also be necessary to correct defects in the bile ducts or to remove parts of the liver that are damaged beyond repair.
