The 13 Causes of Canker Sore (You Should Definitely Be Aware Of)

Autoimmune Disorders

Autoimmune disorders occur when the body’s immune system attacks healthy tissue. Certain autoimmune diseases have been linked to complex and chronic canker sores, including pemphigus and Behcet’s disease. 

Pemphigus is a collection of rare autoimmune skin disorders that cause blisters on the skin and mucous membranes and canker sores. The most common form of pemphigus is pemphigus vulgaris, which typically affects middle-aged adults. Pemphigus can be caused by various factors, including infections and medications. Symptoms of pemphigus include blistering of the mouth, as evidenced by canker sores. Treatment for pemphigus typically involves using steroids, immunosuppressive drugs, or other medications.

Behcet’s disease is a rare autoimmune disorder that can cause inflammation in the blood vessels throughout the body. This can lead to inflammation in the eyes, joints, and brain and sores on the genitals, skin, and mouth. The most common symptom of Behcet’s disease is canker sores that can be extremely painful and make it difficult to eat or drink. Canker sores are one of the most common reasons people with Behcet’s disease seek medical treatment. There is no cure for Behcet’s disease, but treatments are available to help manage symptoms and prevent complications.