Genetics
Medical organizations believe genetics play a role in forming certain types of arthritis. However, the relationship between the disease and genetics is not yet known. But a look at their family histories suggests that the risk increases if a family member has a specific type of arthritis. According to research, genetic markers are linked to certain forms of rheumatoid arthritis.
Another form that has links to genetics is gout. The disorder involves the production and elimination of uric acid. It can be due to the mutations of some markers affecting hereditary hyperuricemia, which impairs the kidneys’ excretion of uric acid.
Researchers are still exploring how genetics influence the development of osteoarthritis. But early results show that the differences in heritability of the disease depend on which joint it affects. The same studies show that genetics have more effect on hip arthritis and spinal arthritis and less on the knee.
Scientists observed that women’s fibromyalgia, rheumatoid arthritis, and osteoarthritis are more prevalent, while men often have gout. However, they are still uncertain why there is a difference in the risk. An expert rheumatologist says that multiple genes are involved, including mutations.
