10 Symptoms Of Liver Damage (Early Warning Signs)

Palmar Erythema and Spider Angiomas

Palmar erythema, otherwise known as liver palms, blotchy red palms, red palms, or Lane’s disease, along with Spider Angiomas or spider naevi or ‘spider webs,’ are also symptoms of advanced liver diseases and liver problems. While palmar erythema may be a rare skin condition, spider angiomas are pretty common. Regardless, both can be a resulting symptom of liver failure. 

As far as palmar erythema is concerned, it stems from the hepatic decompensation resulting from dilated capillaries associated with the increased level of estrogen and estradiol. This results in drawing more blood into the skin’s surface, hence, the rash-like reddening in the palms. 

On the other hand, spider angiomas or spider naevi are red marks caused by blood vessels that draw blood right under the skin. It’s also another strong indicator of liver problems. It appears when the liver function deteriorates, resulting in esophageal variceal bleeding. Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) are also observed to cause ‘spider webs’ in patients with liver cirrhosis, according to a study.